Cooking meatloaf to the proper internal temperature is crucial for food safety to prevent foodborne illness. The safe internal temperature for cooked ground meat, including meatloaf, is 160 degrees Fahrenheit (71 degrees Celsius). At this temperature, harmful bacteria are destroyed, ensuring the meatloaf is safe to consume.
Using a meat thermometer to measure the internal temperature of the meatloaf is the most accurate method to ensure it has reached the safe internal temperature. Insert the thermometer into the thickest part of the meatloaf, avoiding any bones or fatty areas. Once the internal temperature reaches 160 degrees Fahrenheit, the meatloaf is fully cooked and ready to be removed from the oven.